CMA: Take a Bow

Governments take a hit as CMA releases report card.

Phospholemman and the cardiac sodium pump: protein kinase C, take a bow.

In excitable tissues, the activity of the plasmalemmal sodium/potassium ATPase (Na/K pump) is vital for the maintenance of normal electrical activity and ion gradients. In cardiac muscle, the transsarcolemmal sodium (Na) gradient established by the Na/K activity is essential not only for generating the rapid upstroke of the action potential but also for driving a number of ion exchange and tran...

CMA package vignette

Moreover, model selection and evaluation of prediction rules proves to be highly difficult in this situation for several reasons. Firstly, the hazard of overfitting, which is common to all prediction problems, is increased by high dimensionality. Secondly, the usual evaluation scheme based on the splitting into learning and test data sets often applies only partially in the case of small sample...

Resistance Prediction for a Novel Trimaran with Wave Piercing Bow

Nowadays, application of high speed crafts with large tonnage is of our country's essences. In order to gain high speed, new multi hull crafts are traditional. A hull form having been used recently in frigates is the Trimaran. Trimaran hull form and motion have been extensively studied due to the development of numerical and analytical methods as well as the exploitation of experimental setup. ...

The CMA Evolution Strategy: A Tutorial

3 Adapting the Covariance Matrix 10 3.1 Estimating the Covariance Matrix From Scratch . . . . . . . . . . . . . . . . 10 3.2 Rank-μ-Update . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.3 Rank-One-Update . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.3.1 A Different Viewpoint . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.3.2 Cumulation: Uti...